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Caelyx

Duxorubicin Hydrochloride

International Name
- Caelyx
Manufacturer
- Schering Plough
Contains
- Duxorubicin Hydrochloride
Packing
- 10ml
Strength
- 2mg/ml
Form
- liquid

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Caelyx is a drug used for chemotherapy treatment of cancer. It contains doxorubicin hydrochloride 2 mg per ml which interact with cells in such a way that it kill particular cancer cell. It is also known as chemotherapy medicines.

CAELYX belongs to a group of medicines called antineoplastic medicines.Doxorubicin hydrochloride is encapsulated inside liposomes that help to deliver the medicine from the blood stream to the cancerous tissue rather than healthy normal tissue This process is called pegylation .It protects detection of liposomes by the mononuclear phagocyte system (MPS) and increase blood circulation time.

Caelyx is used in treatment for breast and ovarian cancer. It is also used in treatment of another type of cancer known as Kaposi’s sarcoma. Caelyx flatten, lighten and reduce the cancer and produces an improvement in Kaposi’s sarcoma. Other symptoms of Kaposi’s sarcoma are swelling around the tumor which may improve or disappear.

It is used to kill cancer cells, reduce the size and slow down the growth of the tumor.

Caelyx should not be consumed in combination with other medicines that contain doxorubicin hydrochloride. It is also used in combination with another medicine called bortezomib to treat multiple myeloma

Caelyx should be given under the supervision of a doctor. It is given into a vein in a drip known as infusion. This may take from 30 minutes to more than one hour depending on the dose. The doctor will decide how much dose and for how long period it should be given.

For breast or ovarian cancer the recommended starting dose of Caelyx is 50 mg per square meter body surface area, calculated according to patient’s body structure, every four weeks as long as the patient can tolerate the treatment.

For Kaposi’s sarcoma, the dose is 20 mg/m2 for two to three months for every two to three weeks

For multiple myeloma, it is 30 mg/m2 on day four of each three-week cycle of bortezomib treatment, for as long as the patient continues to benefit from the treatment and can tolerate it.

Be attentive when you drive or operate machinery .It may cause dizziness or tiredness.

Side Effects

Some common side-effects are:

• Tiredness, sleepiness

• Loss of appetite, weight loss

• Stomach- aches, diarrhea, vomiting nausea and constipation

• Loss of hair, rashes on skin

• Depression or anxiety

• Back paining and soaring of muscles

• Swollen face, lips, mouth or throat

• Hives or nettle rash

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