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Pioglitazone hydrochloride is used to control high blood sugar in type 2 diabetes. This form of the illness usually stems from the body’s inability to make good use of insulin, the natural hormone that helps to transfer sugar out of the blood and into the cells, where it’s converted to energy. Pioglitazone hydrochloride works by improving the body’s response to its natural supply of insulin, rather than increasing its insulin output. Pioglitazone hydrochloride also reduces the production of unneeded sugar in the liver.

Pioglitazone hydrochloride (and the similar drug Avandia) can be used alone or in combination with insulin injections or other oral diabetes medications such as DiaBeta, Micronase, Glucotrol, or Glucophage. Most important fact about Pioglitazone hydrochloride Always remember that Pioglitazone hydrochloride is an aid to, not a substitute for, good diet and exercise. Failure to follow a sound diet and exercise plan can lead to serious complications, such as dangerously high or low blood sugar levels. Remember, too, that Pioglitazone hydrochloride is not an oral form of insulin, and cannot be used in place of insulin.

How should you take Pioglitazone hydrochloride?

Pioglitazone hydrochloride should be taken once a day with or without meals. –If you miss a dose… Take it as soon as you remember. If you miss a dose on one day, skip it and go back to your regular schedule. Do not double your dose the following day. –Storage instructions… Store at room temperature in a tight container, away from moisture and humidity. What side effects may occur? Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Pioglitazone hydrochloride. More common side effects may include: Headache, hypoglycemia, muscle aches, respiratory tract infection, sinus inflammation, sore throat, swelling, tooth disorder

Why should Pioglitazone hydrochloride not be prescribed?

If Pioglitazone hydrochloride gives you an allergic reaction, you should not take Pioglitazone hydrochloride. Special warnings about Pioglitazone hydrochloride In very rare cases, a drug similar to Pioglitazone hydrochloride has proven toxic to the liver. The manufacturer therefore recommends that your doctor check your liver function before you begin taking Pioglitazone hydrochloride and periodically thereafter. If you experience symptoms of liver problems such as jaundice (yellowing of the skin and eyes), nausea, vomiting, abdominal pain, fatigue, loss of appetite, or dark urine, report them to your doctor immediately. You will probably have to stop using Pioglitazone hydrochloride. Because Pioglitazone hydrochloride works by improving the body’s response to its own supply of insulin, it is not for type 1 diabetics, who are unable to produce any insulin at all. For the same reason, Pioglitazone hydrochloride can’t be used to treat the condition known as diabetic ketoacidosis (excessively high sugar levels due to the lack of insulin).

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