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International Name :
Glibenclamide 5mg
Active Ingredient :
Glibenclamide 5mg
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This belongs to the group of medicines known as oral antidiabetics.

Glibenclamide is be used to treat Type 2 (non-insulin dependent) diabetes mellitus.

Insulin is made naturally in the pancreas. It regulates the amount of sugar in the blood. If the body does not make enough insulin to meet its needs, or does not properly use the insulin it makes, this results in the condition called diabetes mellitus (sugar diabetes).

Glibenclamide works by increasing the amount of insulin that the pancreas secretes.

Glibenclamide is available in tablet form.

It is also sometimes known as: Daonil; Diabetamide; Euglucon; Semi-Daonil. You may notice the use of any of these names on the packaging of your medicine.
How to Take Glibenclamide

Take Glibenclamide exactly as directed by your doctor.
Always read the printed information leaflet, if possible before beginning treatment.
Try to take this medicine at the same time each day to avoid missing any doses.
At the start of treatment your vision may be affected (e.g.blurred) for a short time; if this happens, do not drive or operate machinery.
Take Glibenclamide with or immediately after breakfast with a glass of water, or as directed by your doctor or diabetic nurse.
If you miss a dose, take it as soon as you remember (with food) and continue taking it at the usual time. If it is nearly time for your next dose, leave out the missed dose; never take two doses at the same time to compensate. If in doubt speak to your pharmacist or doctor.
Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of Glibenclamide go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if empty.
Glibenclamide is for you. Never give it to others even if their condition appears to be the same as yours.
Getting the most from your treatment

Before taking any ‘over-the-counter’ medicines, check with your pharmacist which medicines are safe for you to take alongside Glibenclamide.
At the start of treatment your vision may be affected (e.g.blurred) for a short time; if this happens, do not drive or operate machinery.
It is IMPORTANT that you follow any dietary instructions that you have been given by your doctor or diabetic nurse.
If you are having any kind of surgery including dental or emergency treatment, tell your dentist, doctor or surgeon you are taking Glibenclamide.
Check with your doctor before taking up any physical exercise, as this will have a long lasting effect on your blood sugar levels.
You must keep your regular appointment with your doctor or diabetic nurse. Your doctor may want to adjust the dose of Glibenclamide you are taking. DO NOT stop taking Glibenclamide without speaking to your doctor or diabetic nurse first.
Your doctor may recommend that you test for sugar in the blood or urine to check your diabetes is being well controlled.
Avoid drinking alcohol on an empty stomach. Alcohol may produce low blood sugar and affects the control of your condition.
Glibenclamide may cause constipation. Constipation can often be eased by eating plenty of fruit and vegetables and by drinking plenty of water.
Hypoglycaemia (low blood sugar)

Hypoglycaemia is likely to occur if you miss a meal, if you exercise more than usual, if you cannot eat because of sickness or if you drink a lot of alcohol.
The symptoms to look out for include anxious feeling, cold sweats, confusion, headache, feeling sick, being sick, nervousness, palpitations (being aware of your heartbeat), shaking, unusual tiredess, weakness or visual problems. Eat something containing sugar such as glucose tablets, biscuits or a sugary drink (not diet) and follow this up with a starchy snack, such as a sandwich to raise your blood sugar.
Check with your doctor or diabetic nurse straight away, because you may get further attacks over the next few days. The dose of your tablets may need to be altered. Severe symptoms of hypoglycaemia such as convulsions and unconsciousness require IMMEDIATE medical attention.
Drivers should take special care on long journeys. If hypoglycaemia occurs, you should wait at least fifteen minutes before continuing on your journey. Driving is not permitted when you are unable to recognise the warning signs of a hypoglycaemic attack.
Hyperglycaemia (high blood sugar)

Symptoms usually appear more slowly then those of low blood sugar. These symptoms may occur if you over eat, if you miss a dose of your medicine, if you do not follow a proper diet, if you have a fever or infection.
Symptoms include drowsiness, flushed face, fruity smell on breath, increased urination (passing water), loss of appetite or unusual thirst. Severe symptoms may include rapid pulse and heavy breathing.
If you experience any of the symptoms mentioned check with your doctor or diabetic nurse immediately.
Can Glibenclamide cause problems?

Along with their needed effects, all medicines can cause unwanted symptoms, which usually improve as your body adjusts to the new medicine. Speak with your doctor if any of the following symptoms continue or become troublesome.

Feeling sick, being sick, weight gain, diarrhoea or constipation.

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