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BONIVA-150 ( Generic Ibandronate-150 )

Ibandronate-150

International Name
- Boniva
Manufacturer
- Roche
Contains
- Ibandronate-150
Packing
- 1 Tablet
Strength
- 150mg
Form
- Tablet

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Boniva alters the cycle of bone formation and breakdown in the body. It slows bone loss while increasing bone mass, which may prevent bone fractures.

Boniva is used to treat or prevent osteoporosis in women after menopause.

Boniva may also be used for purposes other than those listed in this medication guide.

Important information about Boniva
Do not take a Boniva tablet if you cannot sit upright or stand for at least one full hour. Boniva can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 60 minutes after taking this medication.

Take the Boniva tablet first thing in the morning, at least 1 hour (60 minutes) before you eat or drink anything or take any other medicine.

Take each dose with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking a Boniva tablet.
For at least the first 60 minutes after taking a Boniva tablet, do not lie down or recline; do not eat or drink anything other than plain water; and do not take any other medicines including vitamins, calcium, or antacids.

Some people using medicines similar to Boniva have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problems.

Boniva is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

What should I discuss with my healthcare provider before using Boniva?
Do not take a Boniva tablet if you cannot sit upright or stand for at least one full hour. Boniva can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 60 minutes after taking this medication.

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have:

low blood calcium (hypocalcemia);

a vitamin D deficiency;

kidney disease; or

an ulcer in your stomach or esophagus.

If you have any of these conditions, you may not be able to use Boniva, or you may need a dosage adjustment or special tests during treatment.

Some people using medicines similar to Boniva have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.

You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and dental surgery or pre-existing dental problems.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medication passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use Boniva?
Use Boniva exactly as it was prescribed for you. Do not use the medication in larger amounts or for longer than recommended by your doctor. Follow the directions on your prescription label.

Boniva tablets are taken either once each day or once each month. Boniva intravenous solution is given as an injection into one of your veins once every three (3) months. Your doctor, nurse, or other healthcare professional will give you the Boniva injection. Boniva tablets can be taken at home.

Take the Boniva tablet first thing in the morning, at least 1 hour (60 minutes) before you eat or drink anything or take any other medicine. If you take a Boniva tablet only once a month, take it on the same day each month and always first thing in the morning.

Take each Boniva tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking a Boniva tablet. Do not crush, chew, or suck the Boniva tablet. Swallow the pill whole.
After taking a Boniva tablet, carefully follow these instructions:

Do not lie down or recline for at least 60 minutes after taking Boniva.
Do not eat or drink anything other than plain water.
Do not take any other medicines including vitamins, calcium, or antacids for at least 60 minutes after taking Boniva. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.
To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.

Boniva is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store Boniva tablets at room temperature away from moisture and heat.
What happens if I miss a dose?
If you take Boniva tablets once daily: If you forget to take this medicine first thing in the morning, do not take it later in the day. Wait until the following morning to take the medicine and skip the missed dose. Do not take take two (2) tablets in one day.

If you take Boniva tablets once a month: If you forget to take this medication on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular monthly schedule on your chosen dose day. If your next scheduled dose is less than 7 days away, wait until then to take the medicine and skip the missed dose. Do not take take two (2) tablets in one week.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.
Symptoms of a Boniva overdose may include nausea, heartburn, pain in the abdomen, diarrhea, muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.

What should I avoid while taking Boniva?
Do not take any other medicines including vitamins, calcium, or antacids for at least 60 minutes after taking a Boniva tablet. Do not lie down for at least 1 hour (60 minutes) after you take a Boniva tablet.
Boniva side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Boniva and call your doctor at once if you have any of these serious side effects:
chest pain;

difficulty or pain when swallowing;

pain or burning under the ribs or in the back;

new or worsening heartburn;

severe joint, bone, or muscle pain; or

jaw pain, numbness, or swelling.

Other less serious side effects are more likely to occur. Continue using this medication and talk with your doctor if you have any of these less serious side effects:

redness or swelling of your eyes;

diarrhea;

flu symptoms;

redness or swelling where the medicine was injected;

nausea or upset stomach; or

pain in your arms or legs.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Boniva?
Antacids, supplements, or medicines that contain aluminum, magnesium, iron or other minerals can interfere with how your body absorbs Boniva. If you use these other medicines, do not that take them for at least 60 minutes after taking a Boniva tablet.

Before using Boniva, tell your doctor if you also use aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as celecoxib (Celebrex), diclofenac (Voltaren), diflunisal (Dolobid), ibuprofen (Motrin, Advil), indomethacin, ketoprofen (Orudis), ketorolac (Toradol), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.

There may be other drugs that can affect Boniva. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?
Your pharmacist has more information about Boniva written for health professionals that you may read.
What does my medication look like?
Ibandronate is available with a prescription under the brand name Boniva. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Boniva 2.5 mg–white, oblong, film-coated tablet

Boniva 150 mg–white, oblong, film-coated tablet

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