Adrenaline (Epinephrine)

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International Name
- Adrenalin
- Epinephrine
- 1 ml
- 1mg
- Injection

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ADRENALINE is a natural hormone free in response to stress. Epinephrine is a natural “antidote” to the chemicals published during severe allergic reactions triggered by food allergy ,drug allergy, or insect allergy. It is destroyed by enzymes in the stomach, and so wants to be this injection. When injection , it rapidly reverses the effects of a severe allergic reaction by reducing throat swelling, opening the airways and maintaining blood pressure. Utilization of adrenaline for treating anaphylaxis is first recourse


  • Sympathomimetics like ventolin & isoprenaline cause additive effects
  • Beta-blockers antagonize therapeutic effects of adrenaline
  • Digitalis potentiates the proarrhythmic effects of adrenaline
  • Phenothiazine causes a paradoxical decrease in blood pressure
  • Monoamine oxidase inhibitors (MOAIs) potentiate the cardiovascular effects of adrenaline

In medicine adrenaline is used to treat:

  • Anaphylaxis
  • Cardiac arrest – stimulates the heart
  • Asthma – acts as a bronchodilator (opens up the airways)
  • Glaucoma – when applied topically to the eyes it decreases intra-ocular pressure
  • Dental analgesia – added to local anaesthetic to reduce bleeding

Side Effects of Adrenaline

  • Anxiety (transient), Fear & Tremor
  • Cold fingers and toes and dry mouth (due to vasoconstriction)
  • Headaches
  • Pallor (“white as a sheet”) – also due to vasoconstriction
  • Cardiac arrhythmias, Angina, and excessive rise in blood pressure
  • Intracerebral bleeding leading to strokes
  • Hyperventilation


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