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PREMARIN – 0.625 Conjugated Estrogen

Conjugated Estrogen

International Name
- PREMARIN - 0.625
Manufacturer
- Wyeth
Contains
- Conjugated Estrogen
Packing
- 28 Tablets
Strength
- 0.625mg
Form
- Tablet

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Contents     :     PREMARIN – 0.625 Conjugated Estrogen
Packing      :     28

Feel Confident With PREMARIN– 0.625 You don’t have to live with hot flashes or night sweats. In extensive studies, PREMARIN was proven to treat moderate to severe menopausal symptoms—and it has over 60 years of experience. PREMARIN, an estrogen, is proven to increase bone mass and help prevent post menopausal osteoporosis (bone loss). If you do not have symptoms, non-estrogen treatments should be carefully considered before taking PREMARIN solely for the prevention of postmenopausal osteoporosis. PREMARIN is not a lifelong commitment, so you won’t be on it forever—just for as long as you need menopausal symptom relief. Learn more about PREMARIN. Important Safety Information What is the most important information you should know about PREMARIN (estrogens), PREMPRO (a combination of estrogens and a progestin), or PREMARIN Vaginal Cream (a cream of estrogens)? Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are using these products. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your health care provider should check any unusual vaginal bleeding to find out the cause. Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens, with or without progestins, may increase your risk of dementia, based on a study of women age 65 years or older. You and your health care provider should talk regularly about whether you still need treatment with estrogens. PREMARIN- 0.625 (conjugated estrogens tablets, USP) is used after menopause to reduce moderate to severe hot flashes; to treat moderate to severe dryness, itching, and burning, in and around the vagina; and to help reduce your chances of getting osteoporosis (thin weak bones). PREMPROTM- 0.625 (conjugated estrogens/medroxyprogesterone acetate tablets) is used after menopause in women with a uterus to reduce moderate to severe hot flashes; to treat moderate to severe dryness, itching, and burning, in and around the vagina; and to help reduce your chances of getting osteoporosis (thin weak bones). PREMARIN® – 0.625(conjugated estrogens) Vaginal Cream is used to treat dryness, itching, and burning, in and around the vagina due to menopause. PREMARIN- 0.625 and PREMPRO should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks. If using PREMARIN or PREMPRO only to treat your symptoms of vaginal dryness, consider topical therapies first. If you do not have symptoms, non-estrogen treatments should be carefully considered before taking PREMARIN- 0.625 and PREMPRO solely for the prevention of postmenopausal osteoporosis. In a clinical trial, the most commonly reported (>5%) side effects that occurred more frequently with PREMARIN – 0.625 than with placebo were vaginitis due to yeast or other causes, vaginal bleeding, painful menstruation, and leg cramps. In a clinical trial, the most commonly reported (>5%) side effects that occurred more frequently with PREMPRO 0.45 mg/1.5 mg and PREMPRO 0.625 mg/2.5 mg than with placebo were breast pain/enlargement, vaginitis due to yeast or other causes, leg cramps, vaginal spotting/bleeding, and painful menstruation. In a clinical trial, there was no difference in the commonly reported (>5%) side effects for women taking PREMPRO 0.3 mg/1.5 mg compared to those taking placebo. The most commonly reported side effects of PREMARIN Vaginal Cream include vaginal discomfort or pain, breast pain, vaginitis, and itching. PREMARIN- 0.625 , PREMPRO, and PREMARIN Vaginal Cream should not be used if you have unusual vaginal bleeding, have or had cancer of the breast or uterus, had a stroke or heart attack in the past year, have or had blood clots, have liver problems, are allergic to any of the ingredients in PREMARIN- 0.625, PREMPRO, or PREMARIN Vaginal Cream, or think you may be pregnant. In general, the addition of a progestin is recommended for women with a uterus to reduce the chance of getting cancer of the uterus.

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